We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies, revised Privacy Policy and Terms of Service.
You are being directed to ZacksTrade, a division of LBMZ Securities and licensed broker-dealer. ZacksTrade and Zacks.com are separate companies. The web link between the two companies is not a solicitation or offer to invest in a particular security or type of security. ZacksTrade does not endorse or adopt any particular investment strategy, any analyst opinion/rating/report or any approach to evaluating individual securities.
If you wish to go to ZacksTrade, click OK. If you do not, click Cancel.
AstraZeneca's Fasenra Meets Endpoint in Rhinosinusitis Study
Read MoreHide Full Article
AstraZeneca (AZN - Free Report) announced that the phase III OSTRO study evaluating its asthma drug, Fasenra (benralizumab) in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) met both co-primary endpoints of reduced nasal polyp size and nasal blockage. Data from the study showed that improvement in the size of nasal polyps and nasal blockage in patients with CRSwNP were statistically significantly versus placebo.
The patients in the study were still symptomatic despite continued treatment with standard of care that primarily consists of intranasal corticosteroids and systemic corticosteroids.
Please note that the OSTRO study is part of AstraZeneca’s clinical program evaluating Fasenra as a potential treatment of CRSwNP. Another ongoing phase III study — ORCHID — is part of the program.
CRSwNP is an inflammatory disease that can lead to elevated levels of eosinophils in the upper respiratory tract and benign growth called nasal polyps. Patients with polyps can suffer from nasal blockage and discharge, reduction or loss in the sense of smell, sleep disturbances and other adverse effects on quality of life. Data from the OSTRO study suggests that these patients may benefit from Fasenra, following a potential label expansion approval for CRSwNP.
AstraZeneca shares have risen 6.4% so far this year compared with the industry’s increase of 0.5%.
Fasenra is currently approved as an add-on maintenance treatment for severe eosinophilic asthma in the United States, Europe, Japan and other countries. It currently faces competition from GlaxoSmithKline’s (GSK - Free Report) Nucala and Teva Pharmaceutical Industries' (TEVA - Free Report) Cinqair. Fasenra also competes with other drugs that are approved to treat asthma including Novartis (NVS - Free Report) /Roche’s Xolair and Sanofi/Regeneron’s, Dupixent. Meanwhile, Roche is also developing Xolair as a potential treatment for CRSwNP.
Fasenra is one of AstraZeneca’s key drugs driving its product sales growth. The drug recorded sales of $426 million in the first half of 2020, representing growth of 43.9% at a constant exchange rate. According to AstraZeneca, Fasenra enjoys leadership position among novel biologic asthma medicines in Europe and Japan.
Meanwhile, AstraZeneca is also developing the drug for chronic obstructive pulmonary disease and other eosinophilic diseases including eosinophilic granulomatosis with polyangiitis, hypereosinophilic syndrome and eosinophilic oesophagitis.
Each was hand-picked by a Zacks expert as the #1 favorite stock to gain +100% or more in 2020. Each comes from a different sector and has unique qualities and catalysts that could fuel exceptional growth.
Most of the stocks in this report are flying under Wall Street radar, which provides a great opportunity to get in on the ground floor.
Image: Bigstock
AstraZeneca's Fasenra Meets Endpoint in Rhinosinusitis Study
AstraZeneca (AZN - Free Report) announced that the phase III OSTRO study evaluating its asthma drug, Fasenra (benralizumab) in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) met both co-primary endpoints of reduced nasal polyp size and nasal blockage. Data from the study showed that improvement in the size of nasal polyps and nasal blockage in patients with CRSwNP were statistically significantly versus placebo.
The patients in the study were still symptomatic despite continued treatment with standard of care that primarily consists of intranasal corticosteroids and systemic corticosteroids.
Please note that the OSTRO study is part of AstraZeneca’s clinical program evaluating Fasenra as a potential treatment of CRSwNP. Another ongoing phase III study — ORCHID — is part of the program.
CRSwNP is an inflammatory disease that can lead to elevated levels of eosinophils in the upper respiratory tract and benign growth called nasal polyps. Patients with polyps can suffer from nasal blockage and discharge, reduction or loss in the sense of smell, sleep disturbances and other adverse effects on quality of life. Data from the OSTRO study suggests that these patients may benefit from Fasenra, following a potential label expansion approval for CRSwNP.
AstraZeneca shares have risen 6.4% so far this year compared with the industry’s increase of 0.5%.
Fasenra is currently approved as an add-on maintenance treatment for severe eosinophilic asthma in the United States, Europe, Japan and other countries. It currently faces competition from GlaxoSmithKline’s (GSK - Free Report) Nucala and Teva Pharmaceutical Industries' (TEVA - Free Report) Cinqair. Fasenra also competes with other drugs that are approved to treat asthma including Novartis (NVS - Free Report) /Roche’s Xolair and Sanofi/Regeneron’s, Dupixent. Meanwhile, Roche is also developing Xolair as a potential treatment for CRSwNP.
Fasenra is one of AstraZeneca’s key drugs driving its product sales growth. The drug recorded sales of $426 million in the first half of 2020, representing growth of 43.9% at a constant exchange rate. According to AstraZeneca, Fasenra enjoys leadership position among novel biologic asthma medicines in Europe and Japan.
Meanwhile, AstraZeneca is also developing the drug for chronic obstructive pulmonary disease and other eosinophilic diseases including eosinophilic granulomatosis with polyangiitis, hypereosinophilic syndrome and eosinophilic oesophagitis.
AstraZeneca PLC Price
AstraZeneca PLC price | AstraZeneca PLC Quote
Zacks Rank
AstraZeneca currently carries a Zacks Rank #3 (Hold). You can see the complete list of today’s Zacks #1 Rank (Strong Buy) stocks here.
5 Stocks Set to Double
Each was hand-picked by a Zacks expert as the #1 favorite stock to gain +100% or more in 2020. Each comes from a different sector and has unique qualities and catalysts that could fuel exceptional growth.
Most of the stocks in this report are flying under Wall Street radar, which provides a great opportunity to get in on the ground floor.
Today, See These 5 Potential Home Runs >>