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Simulations Plus (SLP) Ties Up With ICCS for Chemical Safety
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Simulations Plus, Inc. (SLP - Free Report) has entered into a partnership with the International Collaboration on Cosmetics Safety (“ICCS”) to develop a physiologically-based kinetic (PBK) read-across strategy for diverse chemicals and exposure routes (intravenous, oral and dermal) across virtual populations of humans and rodents. This collaboration aims to establish procedural workflows and guidelines for integrating these methods into animal-free safety assessments.
ICCS, based in New York, advocates for animal-free assessments in cosmetics worldwide, prioritizing human and environmental safety. Despite global bans on animal tests, some regions still require them and do not accept animal-free data, driving the need for animal data even for viable alternatives. ICCS aims to meet regulatory needs by promoting innovative, animal-free solutions. By using advanced technologies like computer models, in-vitro testing and data analysis, ICCS ensures safe cosmetic products without animal testing, benefiting both consumers and the environment.
Simulations Plus offers physiologically-based pharmacokinetic modeling and consulting services using GastroPlus software, recognized in the pharmaceutical industry for predicting drug absorption and disposition in humans and animals. They are pioneers in merging machine learning with PBK models, using limited in vitro data to accurately predict safety exposure levels.
In their newly funded research project, Simulations Plus will assess the data from ICCS, select target-source pairs based on similarity criteria, create PBK models for source chemicals, and use these to predict exposure levels in virtual populations for target chemicals. Their discoveries and recommended practices will be shared publicly, providing essential guidance for companies and regulatory bodies.
Simulations Plus is a leading-edge developer of simulation software for pharmaceutical, chemical and biotechnology companies across the globe. The simulation software is used for drug discovery, development, research and regulatory submissions.
SLP currently carries a Zacks Rank #4 (Sell). Shares of the company have lost 12.1% in the past year against the industry’s growth of 31.2%.
Image Source: Zacks Investment Research
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NVIDIA is the worldwide leader in visual computing technologies and the inventor of the graphic processing unit. Over the years, the company’s focus evolved from PC graphics to AI-based solutions that support high-performance computing, gaming and virtual reality platforms.
Onto Innovation Inc. (ONTO - Free Report) , carrying a Zacks Rank #2 (Buy) at present, delivered an earnings surprise of 2.7%, on average, in the trailing four quarters.
Headquartered in Wilmington, MA, Onto Innovation specializes in the design, development, manufacture and support of metrology and inspection tools primarily for semiconductor device fabricators, silicon wafer manufacturers and advanced packaging manufacturers in the semiconductor space.
Cirrus Logic, Inc. (CRUS - Free Report) , carrying a Zacks Rank #2 at present, delivered an earnings surprise of 52.3%, on average, in the trailing four quarters.
Based in Austin, TX, Cirrus Logic is a fabless semiconductor supplier known for its low-power, high-precision mixed-signal processing solutions. They focus on smartphone audio leadership, enhancing mixed-signal content in smartphones, and exploring new market opportunities.
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Simulations Plus (SLP) Ties Up With ICCS for Chemical Safety
Simulations Plus, Inc. (SLP - Free Report) has entered into a partnership with the International Collaboration on Cosmetics Safety (“ICCS”) to develop a physiologically-based kinetic (PBK) read-across strategy for diverse chemicals and exposure routes (intravenous, oral and dermal) across virtual populations of humans and rodents. This collaboration aims to establish procedural workflows and guidelines for integrating these methods into animal-free safety assessments.
ICCS, based in New York, advocates for animal-free assessments in cosmetics worldwide, prioritizing human and environmental safety. Despite global bans on animal tests, some regions still require them and do not accept animal-free data, driving the need for animal data even for viable alternatives. ICCS aims to meet regulatory needs by promoting innovative, animal-free solutions. By using advanced technologies like computer models, in-vitro testing and data analysis, ICCS ensures safe cosmetic products without animal testing, benefiting both consumers and the environment.
Simulations Plus offers physiologically-based pharmacokinetic modeling and consulting services using GastroPlus software, recognized in the pharmaceutical industry for predicting drug absorption and disposition in humans and animals. They are pioneers in merging machine learning with PBK models, using limited in vitro data to accurately predict safety exposure levels.
In their newly funded research project, Simulations Plus will assess the data from ICCS, select target-source pairs based on similarity criteria, create PBK models for source chemicals, and use these to predict exposure levels in virtual populations for target chemicals. Their discoveries and recommended practices will be shared publicly, providing essential guidance for companies and regulatory bodies.
Simulations Plus is a leading-edge developer of simulation software for pharmaceutical, chemical and biotechnology companies across the globe. The simulation software is used for drug discovery, development, research and regulatory submissions.
SLP currently carries a Zacks Rank #4 (Sell). Shares of the company have lost 12.1% in the past year against the industry’s growth of 31.2%.
Image Source: Zacks Investment Research
Stocks to Consider
NVIDIA Corporation (NVDA - Free Report) , sporting a Zacks Rank #1 (Strong Buy) at present, delivered a trailing four-quarter earnings surprise of 18.4%, on average. In the last reported quarter, it delivered an earnings surprise of 11.5%. It has a long-term earnings growth expectation of 37.6%. You can see the complete list of today’s Zacks #1 Rank stocks here.
NVIDIA is the worldwide leader in visual computing technologies and the inventor of the graphic processing unit. Over the years, the company’s focus evolved from PC graphics to AI-based solutions that support high-performance computing, gaming and virtual reality platforms.
Onto Innovation Inc. (ONTO - Free Report) , carrying a Zacks Rank #2 (Buy) at present, delivered an earnings surprise of 2.7%, on average, in the trailing four quarters.
Headquartered in Wilmington, MA, Onto Innovation specializes in the design, development, manufacture and support of metrology and inspection tools primarily for semiconductor device fabricators, silicon wafer manufacturers and advanced packaging manufacturers in the semiconductor space.
Cirrus Logic, Inc. (CRUS - Free Report) , carrying a Zacks Rank #2 at present, delivered an earnings surprise of 52.3%, on average, in the trailing four quarters.
Based in Austin, TX, Cirrus Logic is a fabless semiconductor supplier known for its low-power, high-precision mixed-signal processing solutions. They focus on smartphone audio leadership, enhancing mixed-signal content in smartphones, and exploring new market opportunities.