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Sanofi Begins Combo Studies on Multiple Myeloma Candidate
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Sanofi, Inc. (SNY - Free Report) announced the start of two new phase III studies evaluating its investigational biologic, isatuximab in combination with other cancer medicines for the treatment of multiple myeloma, a rare blood cancer.
While the first study – IKEMA (n=325) – will compare a combination of isatuximab, Amgen’s (AMGN - Free Report) Kyprolis (carfilzomib) and dexamethasone to Kyprolis and dexamethasone, the second study IMROZ (n=425) will evaluate a combination of isatuximab, dexamethasone, Celgene’s multiple myeloma drug Revlimid (lenalidomide) and Japanese firm Takeda’s Velcade (bortezomib) against a combination of Velcade, Revlimid and dexamethasone.
While the IKEMA study will include patients with relapsed/refractory multiple myeloma that have been previously been treated with one-to-three lines of therapy, IMROZ will evaluate the cancer combinations in newly diagnosed multiple myeloma patients not eligible for transplant.
The primary endpoint will be progression-free survival in both the studies
Please note that isatuximab is already being evaluated as a monotherapy in phase III studies for relapsed/refractory multiple myeloma and in phase II for acute lymphoblastic leukemia.
Sanofi’s shares have risen 7% so far this year, comparing unfavorably with a gain of 14.7% recorded by the industry.
Shares of J&J have risen 21.5% this year so far while 2018 earnings estimates have gone up 1.7% in the past 60 days.
Wall Street’s Next Amazon
Zacks EVP Kevin Matras believes this familiar stock has only just begun its climb to become one of the greatest investments of all time. It’s a once-in-a-generation opportunity to invest in pure genius.
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Sanofi Begins Combo Studies on Multiple Myeloma Candidate
Sanofi, Inc. (SNY - Free Report) announced the start of two new phase III studies evaluating its investigational biologic, isatuximab in combination with other cancer medicines for the treatment of multiple myeloma, a rare blood cancer.
While the first study – IKEMA (n=325) – will compare a combination of isatuximab, Amgen’s (AMGN - Free Report) Kyprolis (carfilzomib) and dexamethasone to Kyprolis and dexamethasone, the second study IMROZ (n=425) will evaluate a combination of isatuximab, dexamethasone, Celgene’s multiple myeloma drug Revlimid (lenalidomide) and Japanese firm Takeda’s Velcade (bortezomib) against a combination of Velcade, Revlimid and dexamethasone.
While the IKEMA study will include patients with relapsed/refractory multiple myeloma that have been previously been treated with one-to-three lines of therapy, IMROZ will evaluate the cancer combinations in newly diagnosed multiple myeloma patients not eligible for transplant.
The primary endpoint will be progression-free survival in both the studies
Please note that isatuximab is already being evaluated as a monotherapy in phase III studies for relapsed/refractory multiple myeloma and in phase II for acute lymphoblastic leukemia.
Sanofi’s shares have risen 7% so far this year, comparing unfavorably with a gain of 14.7% recorded by the industry.
Sanofi carries a Zacks Rank #4 (Sell).
A better-ranked large-cap pharma stock is Johnson & Johnson (JNJ - Free Report) , carrying a Zacks Rank #2 (Buy). You can see the complete list of today’s Zacks #1 Rank (Strong Buy) stocks here.
Shares of J&J have risen 21.5% this year so far while 2018 earnings estimates have gone up 1.7% in the past 60 days.
Wall Street’s Next Amazon
Zacks EVP Kevin Matras believes this familiar stock has only just begun its climb to become one of the greatest investments of all time. It’s a once-in-a-generation opportunity to invest in pure genius.
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