We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies, revised Privacy Policy and Terms of Service.
You are being directed to ZacksTrade, a division of LBMZ Securities and licensed broker-dealer. ZacksTrade and Zacks.com are separate companies. The web link between the two companies is not a solicitation or offer to invest in a particular security or type of security. ZacksTrade does not endorse or adopt any particular investment strategy, any analyst opinion/rating/report or any approach to evaluating individual securities.
If you wish to go to ZacksTrade, click OK. If you do not, click Cancel.
Lilly Reports Mixed Results from Late-Stage Cyramza Study
Read MoreHide Full Article
Eli Lilly and Company (LLY - Free Report) announced top-line data from the phase III study – RAINFALL – evaluating Cyramza (ramucirumab) as first-line treatment for patients with advanced gastric cancer. The study met its primary endpoint of progression free survival ("PFS") but failed to improve overall survival ("OS"). The results will be presented at a future medical meeting.
The company has also announced that it will not seek regulatory approval in the first-line setting based on the data from this study.
Cyramza is presently approved as a single agent or in combination with chemotherapy drug, paclitaxel, for treating advanced or metastatic gastric (stomach) or gastroesophageal junction (“GEJ”) adenocarcinoma in patients whose disease has progressed after prior therapies. The drug is also approved for treating metastatic non-small cell lung cancer and for metastatic colorectal cancer (with tradename Folfiri).
Shares of Lilly have gained 6.9% in the past six months, outperforming the industry’s rise of 4.5% in that period.
The RAINFALL study evaluated Cyramza in combination with cisplatin and capecitabine or 5-fluorouracil as first-line treatment for HER2-negative metastatic gastric or GEJ adenocarcinoma versus a placebo
The company was hopeful that the positive PFS would lead to an OS benefit. Treating advanced gastric cancer is a challenge, which is further underscored by the fact that no major advances over chemotherapies have been achieved for treating metastatic gastric cancer.
Moreover, initial data from another phase III study on Cyramza presented at ESMO 2017 Congress showed that the drug met PFS endpoint in patients with advanced urothelial carcinoma.
Per the press release, gastric cancer is the fifth most common form of cancer in the world. The disease is expected to affect 28,000 new patients and cause 11,000 deaths in the United Sates in 2017 alone.
J&J’s earnings estimates increased from $7.19 to $7.28 for 2017 and from $7.75 to $7.85 over the last 60 days. The company delivered a positive earnings surprise in all the trailing four quarters with an average beat of 3.12%. The company’s shares have returned 22% so far this year.
ACADIA’s loss estimates narrowed from $2.44 to $2.41 for 2017 and from $1.67 to $1.59 over the last 30 days. The company came up with a positive earnings surprise in three of the trailing four quarters with an average beat of 9.95%. The company’s shares have returned 5.7% so far this year.
Corcept’s earnings per share estimates have increased from 78 cents to 88 cents for 2018 over the last 60 days. The company delivered a positive earnings surprise in two of the trailing four quarters with an average beat of 14.32%. The company’s stock is up 131.3% so far this year.
Today's Stocks from Zacks' Hottest Strategies
It's hard to believe, even for us at Zacks. But while the market gained +18.8% from 2016 - Q1 2017, our top stock-picking screens have returned +157.0%, +128.0%, +97.8%, +94.7%, and +90.2% respectively.
And this outperformance has not just been a recent phenomenon. Over the years it has been remarkably consistent. From 2000 - Q1 2017, the composite yearly average gain for these strategies has beaten the market more than 11X over. Maybe even more remarkable is the fact that we're willing to share their latest stocks with you without cost or obligation.
Image: Bigstock
Lilly Reports Mixed Results from Late-Stage Cyramza Study
Eli Lilly and Company (LLY - Free Report) announced top-line data from the phase III study – RAINFALL – evaluating Cyramza (ramucirumab) as first-line treatment for patients with advanced gastric cancer. The study met its primary endpoint of progression free survival ("PFS") but failed to improve overall survival ("OS"). The results will be presented at a future medical meeting.
The company has also announced that it will not seek regulatory approval in the first-line setting based on the data from this study.
Cyramza is presently approved as a single agent or in combination with chemotherapy drug, paclitaxel, for treating advanced or metastatic gastric (stomach) or gastroesophageal junction (“GEJ”) adenocarcinoma in patients whose disease has progressed after prior therapies. The drug is also approved for treating metastatic non-small cell lung cancer and for metastatic colorectal cancer (with tradename Folfiri).
Shares of Lilly have gained 6.9% in the past six months, outperforming the industry’s rise of 4.5% in that period.
The RAINFALL study evaluated Cyramza in combination with cisplatin and capecitabine or 5-fluorouracil as first-line treatment for HER2-negative metastatic gastric or GEJ adenocarcinoma versus a placebo
The company was hopeful that the positive PFS would lead to an OS benefit. Treating advanced gastric cancer is a challenge, which is further underscored by the fact that no major advances over chemotherapies have been achieved for treating metastatic gastric cancer.
Moreover, initial data from another phase III study on Cyramza presented at ESMO 2017 Congress showed that the drug met PFS endpoint in patients with advanced urothelial carcinoma.
Per the press release, gastric cancer is the fifth most common form of cancer in the world. The disease is expected to affect 28,000 new patients and cause 11,000 deaths in the United Sates in 2017 alone.
Eli Lilly and Company Price
Eli Lilly and Company Price | Eli Lilly and Company Quote
Zacks Rank & Stocks to Consider
Lilly carries a Zacks Rank #3 (Hold).
Some better-ranked stocks in the pharma sector include Johnson & Johnson (JNJ - Free Report) , ACADIA Pharmaceuticals Inc. (ACAD - Free Report) and Corcept Therapeutics Inc. (CORT - Free Report) . All the stocks carry a Zacks Rank #2 (Buy). You can see the complete list of today’s Zacks #1 Rank (Strong Buy) stocks here.
J&J’s earnings estimates increased from $7.19 to $7.28 for 2017 and from $7.75 to $7.85 over the last 60 days. The company delivered a positive earnings surprise in all the trailing four quarters with an average beat of 3.12%. The company’s shares have returned 22% so far this year.
ACADIA’s loss estimates narrowed from $2.44 to $2.41 for 2017 and from $1.67 to $1.59 over the last 30 days. The company came up with a positive earnings surprise in three of the trailing four quarters with an average beat of 9.95%. The company’s shares have returned 5.7% so far this year.
Corcept’s earnings per share estimates have increased from 78 cents to 88 cents for 2018 over the last 60 days. The company delivered a positive earnings surprise in two of the trailing four quarters with an average beat of 14.32%. The company’s stock is up 131.3% so far this year.
Today's Stocks from Zacks' Hottest Strategies
It's hard to believe, even for us at Zacks. But while the market gained +18.8% from 2016 - Q1 2017, our top stock-picking screens have returned +157.0%, +128.0%, +97.8%, +94.7%, and +90.2% respectively.
And this outperformance has not just been a recent phenomenon. Over the years it has been remarkably consistent. From 2000 - Q1 2017, the composite yearly average gain for these strategies has beaten the market more than 11X over. Maybe even more remarkable is the fact that we're willing to share their latest stocks with you without cost or obligation.
See Them Free>>